The three Halliwell sisters have always been different, not just from the world around them, but from each other. Though bound together by blood and destiny, these twentysomething women could not be further apart. The oldest, Prue (Shannen Doherty, "Beverly Hills, 90210," "Heathers"), determinedly driven to succeed in life, disdains the free-spirited eccentricities of Phoebe (Alyssa Milano, "Who’s The Boss?" "Melrose Place"), the youngest of the three. Piper (Holly Marie Combs, "Picket Fences"), the earthy and creative middle sister, believes life is best navigated with a sense of humor and often finds herself in the role of mediator between the other two.

The siblings were willed the house of their childhood, which they inharmoniously share, a grand and mysterious Victorian manor that has been in their family for untold generations and defines the term "fixer-upper." Yet, the discovery that these three sisters are powerful good witches, foretold as the "Charmed Ones," creates a bond that reaches far beyond petty sisterly grudges. They must band together to keep their otherworldly witchcraft a secret and vanquish all comers. Complicating matters this fall is Piper’s romantic relationship with Leo (Brian Krause) as it takes a surprising turn.

Created by Constance M. Burge ("Savannah"), the series is produced by Spelling Television. Aaron Spelling and E. Duke Vincent ("7th Heaven," "Beverly Hills, 90210," "Melrose Place") serve as executive producers along with Brad Kern ("Hill Street Blues," "Lois & Clark: The New Adventures of Superman," "New York Undercover").